Call for Papers: Special Issue on Advances in Cancer Research. Submit your manuscript by End of May.
Invitation for Contributions: International Conference on Public Health. Abstract submission deadline extended to 15th June.
Submit Your Research: Journal of Fatima Jinnah Medical University welcomes submissions on emerging topics in healthcare. Deadline: 15th May
Risk factors associated with early variceal rebleed after endoscopic variceal band ligation in cirrhotic Hepatitis B and C patients with variceal bleed

Risk factors associated with early variceal rebleed after endoscopic variceal band ligation in cirrhotic Hepatitis B and C patients with variceal bleed

Risk factors associated with early rebleed in cirrhotic patients

Authors

  • Atif Nasrullah Jinnah Hospital Lahore
  • Muhammad Kashif Assistant Professor of Medicine CMH Lahore Medical College, Combined Military Hospital Lahore
  • Haris Nasrullah
  • Arif Mahmood Saddiqiui JINNAH HOSPITAL LAHORE

DOI:

https://doi.org/10.37018/PENC3048

Keywords:

Cirrhosis, Variceal bleed, Endoscopic variceal band ligation, Rebleeding, risk factors, Association

Abstract

Background: Chronic liver disease is endemic in Pakistan with esophageal variceal bleeding as one of the important complications and is treated with EVBL. The early esophageal variceal rebleeding is one of the ignored factors which carries the high mortality and morbidity.

Patients and methods: This case-control study was conducted in the Gastroenterology Department at Jinnah Hospital, Lahore, from February 2016 to February 2017. The Study included total 100 patients and out of these 50 were rebleeding cases while 50 were controls (without esophageal rebleed). Cases and control were matched for age, sex, Presence of hepatitis B and C and cirrhosis. The endoscopic findings of any active bleed and white nipple sign was recorded.

Results: In this study, association of risk factors for prediction of early variceal rebleed after banding in cirrhotic hepatitis b and c patients with variceal bleed was recorded as 58%(n=29) in cases and 12%(n=6) for active bleeding, O.R was 10.12, 68%(n=34) in cases and 14%(n=7) in controls had nipple sign, O.R was 13.05, Hb level <9 g/dl was recorded in 88%(n=44) in cases and 40%(n=20) in controls, O.R 11.00, PT>18 sec was recorded in 96%(n=48) in cases and 4%(n=2) in controls, O.R was 576.00.

Conclusion: Active bleeding and nipple sign, Hb level < 9 g/dl and PT > 18 sec are found to have strong association for prediction of early variceal rebleed after EVBL in cirrhotic hepatitis B and C patients.

Downloads

Published

2020-03-14

How to Cite

1.
Nasrullah A, Kashif M, Nasrullah H, Saddiqiui AM. Risk factors associated with early variceal rebleed after endoscopic variceal band ligation in cirrhotic Hepatitis B and C patients with variceal bleed: Risk factors associated with early rebleed in cirrhotic patients. J Fatima Jinnah Med Univ [Internet]. 2020 Mar. 14 [cited 2024 Jul. 22];14(1):30-3. Available from: https://www.jfjmu.com/index.php/ojs/article/view/591