Drotaverine for Acceleration of Labour with Reduced Incidence of Caerserean Section and No Postpartum Haemorrhage
Keywords:
Acceleration of Labour, Drotaverine, Caesarean SectionAbstract
Aims & Objectives: To compare the outcome in labouring patients receiving drotaverine versus control group.
Setting: Department of Obs & Gynae Unit-III Services Hospital, Lahore. Study Design: Randomized controlled drug trial.
Sampling Technique: Simple Random sampling.Duration of Study:12-10-14 to 11-04-15
Subjects and Methods: A total of 200 patients (100 in each group) were included in the study. group-A was given 40mg of intravenous drotaverine in first stage of labour during active phase and its effect was assessed by calculating the time in minutes to reach the full dilatation of cervix while group-B did not receive any drug and used as control group. The dose was repeated after 2 hours, if the rate of dilatation of cervix was less than 1cm/hr in primigravida and 1.5cm/hr in multigravida. Patients were monitored in postnatal period in first 24 hours for postpartum haemorrhage in both the groups as per operational definitions. Results were recorded on spss version for final analysis.
Results: patients were ranged between 20-40 years of age. Mean age of the patients was 22.51±4.70 and 26.20±4.55 years in group-A and B, respectively. Mean gestational age was 39.35±1.08 weeks in group-A and 39.59±0.99 weeks in group-B. Postpartum haemorrhage was occurred in 13 patients (13.0%) of group-A and 14 patients (14.0%) of group-B. In group-A, 93 patients (93.0%) and in group-B, 76 patients (76.0%) vaginal delivery performed while in 7 patients (7.0%) of group-A and in 24 patients (24.0%) of group-B caesarean section was carried out. There was statistically significant difference between the two groups (p=0.001). In group-A 56 ladies (56.0%) and in group-B 51 ladies (51.0%) were primigravida while 44 ladies (44.0%) in group-A and 49 ladies (49.0%) in group-B were multigravida. Mean duration of first stage of labour was 206.80±24.45 and 308.40±48.69 in group-A and B, respectively (p<0.001). Stratification with regard to parity was carried out.
Conclusion: In Conclusion, The Use Of Drotaverine Hydrochloride During The active phase of first Stage Of Labor Is safe And Effective In Accelerating Labour. Its timely Administration during first stage of labour helps in faster and smooth progress Of Labor With faster Cervical Dilatation and minimal side effects.
Downloads
Published
How to Cite
Issue
Section
License
The Journal of Fatima Jinnah Medical University follows the Attribution Creative Commons-Non commercial (CC BY-NC) license which allows the users to copy and redistribute the material in any medium or format, remix, transform and build upon the material. The users must give credit to the source and indicate, provide a link to the license, and indicate if changes were made. However, the CC By-NC license restricts the use of material for commercial purposes. For further details about the license please check the Creative Commons website. The editorial board of JFJMU strives hard for the authenticity and accuracy of the material published in the journal. However, findings and statements are views of the authors and do not necessarily represent views of the Editorial Board.